Which ala gly was repeated times within the polypeptide
(5 points) When the tetrameric Hb4 molecule of hemoglobin binds O2, the conformation is driven from the T-state to the R-state.
When O2 binds to hemoglobin, it undergoes conformational changes that are called “cooperative.” Explain the meaning of “cooperative” in the context of hemoglobin.
Suppose a pregnant woman were to go to the top of a mountain for several days. Would the Hb in the fetus that she is carrying in her uterus undergo the same changes that the woman’s Hb would undergo? If there are differences, describe them.
(10 points) You have a simple chemical reaction (A → B). In the direction as written, this reaction is endergonic and exothermic.
What effect would the temperature change have on the sign of ΔH?
(5 points) For a reaction that can take place with or without catalysis by an enzyme, what would be the effect of the enzyme on the: (write; increase, decrease or no change for each)
(5 points) The fats isolated from beef are typically solid at room temperature, whereas the fats isolated from many vegetables are liquid at both room temperature and refrigerator temperatures. Provide a biochemical explanation, including important structural features, as to why the beef fats are solid, and the vegetable fats are liquid.
The number of structurally different polysaccharides that can be made with 20 different monosaccharides is far greater than the number of different polypeptides that can be made with 20 different amino acids if both polymers contain an equal number (say 100) of total residues. Explain why.