Introduction: Insulin, a protein hormone obtained from the Pancreases of pig or by recombinant technology is used to regulate the amount of blood glucose or sugar level. Deviation in blood sugar levels can result in Diabetes mellitus Type1 and Type2, Gestational diabetes. Glucagon, an antagonist hormone to insulin is used by the body to maintain the blood sugar level-so that cells are rejuvenated with enough glucose to gain energy.
Insulin was first used in medical science in 1922 in Canada by Charles Best, James Collip and Fredrick Banting. Taking into consideration it's efficacy and safety in health science, insulin has been listed amongst essential Medicines by World Health Organization.
Types of insulin: Depending on its action, onset, duration and peak insulin can be broadly classified into
Sl No |
Type of action |
The onset of function in minutes |
Duration in hours |
|
1 |
Rapid |
15 |
3-5 |
|
2 |
Short |
30-60 |
5 - 8 |
|
3 |
Intermediate |
60 - 180 |
12 - 16 |
|
4 |
Long |
60 |
20 - 26 |
|
5 |
Premixed |
Combination of rapid or short-acting with that of Long-acting. |
Mode of insulin therapy:
A person with Type 1 diabetes needs regular insulin therapy but the treatment regime varies. Insulin delivery may be through
Doses vary according to the need of the patient and in a few cases, extra shots of rapid and short-acting insulin may be required at mealtime.
Side effects and complications involving the intake of insulin:
Persons might experience few side effects due to insulin therapy, like
Faulty intake or uncontrolled schedule of insulin intake may lead to
Route of administration: Generally, insulin is administered subcutaneously. Depending on variants, it can also be used through Intravenous or Intramuscular route.
Conclusion:
As the world is indulged in faulty dietary habits and busy lifestyles, diabetes engulfs a larger proportion of the population under its effect as such Insulin therapy is a boon to medical science. A diabetic person should stick to a controlled schedule regarding insulin intake along with the right type.
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